The Antibacterial Activity of Acanthus ilicifolius L. n-Hexane Fraction

Background: Recently, with the high prevalence of diarrhoea caused by bacterial infection, usage antibiotics has increased. Antibiotic overuse might lead to several side effects and resistance, suggesting development an alternate antibacterial agent. A mangrove plant, Acanthus Illinois, contained triterpenoid, which properties.
 Aim: This study aimed evaluate effect Illinois n-hexane fraction against Escherichia coli Shigella dysenteriae.
 Method: The was using n-Hexane, identification secondary metabolite compound GC-MS, evaluation activity dysenteriae under paper disc methods. designed a fully randomized design (CRD) concentrations fractions 1%, 2%, 4%. GC-MS results were compared WILEY 9 library analysed. prism graph used measure inhibition zone activity.
 Result: yield is 3.3% contains sesquiterpene compounds (trans (beta.)-caryophyllene, alpha humulene, naphthalene decahedron-4A-methyl), terpenoid alcohol (3,7,11,15-tetramethyl -2-hexadecane-1-ol), fatty acids (hexadecanoic acid methyl ester. in dose-dependent manner. 
 Conclusion: leaves ilicifolius sesquiterpene, terpenoids, fatty,